Program Overview
This CME/CE program is derived from content presented at the Maui Derm for Dermatologists 2022 Annual Meeting. The expert faculty, led by Lawrence Eichenfield, MD, will highlight the use of Janus kinases (JAK) inhibitor therapeutics to improve outcomes in patients with atopic dermatitis. The faculty will begin with an overview of current clinical trial data, including new and emerging therapies utilizing JAK-1 inhibitors, for the treatment of atopic dermatitis. Following, the practical applications of JAK-1 inhibitor therapeutics, pertaining to vaccinations and mitigating risk, will be analyzed. The faculty will conclude with a series of challenging cases presentations for improving outcomes for patients with atopic dermatitis.
Target Audience
Dermatologists, and dermatology advanced practice providers (NPs and PAs) who are involved in the care and treatment of patients with moderate-to-severe atopic dermatitis
Learning Objectives
- Understand the disease burden and therapeutic targets, including the JAK-1 receptor, for moderate-to-severe atopic dermatitis
- Review recent JAK-1 inhibitor clinical trial data for the management of adolescents and adults with moderate-to-severe atopic dermatitis
- Develop comprehensive treatment plans including a risk-benefit profile for JAK-1 receptor therapeutics and appropriate vaccinations to apply monoclonal antibody therapies to treat AD
Agenda
I. Atopic Dermatitis Clinical Trial Update: New and Emerging Therapies Including JAK-1 Inhibitors – Lawrence Eichenfield, MD
II. Practical Applications of JAK-1 Inhibitor Therapeutics – Vaccinations and Mitigating Risk – Jonathan Silverberg, MD, PhD
III. Challenging Patient Case Series for Improving Outcomes for Patients with Moderate to Severe Atopic Dermatitis – Eric Simpson, MD & Alyssa Wu, PharmD
Faculty
Lawrence F. Eichenfield, MD (Course Chair)
Distinguished Professor of Dermatology and Pediatrics
Vice Chair, Department of Dermatology
Chief, Pediatric and Adolescent Dermatology
University of California, San Diego
Rady Children’s Hospital, San Diego
San Diego, CA
Jonathan Silverberg, MD, PhD, MPH
Associate Professor
Director of Clinical Research
Director of Patch Testing
George Washington University School of Medicine and Health Sciences
Washington, DC
Eric Simpson, MD, MCR
Professor of Dermatology
Department of Dermatology Oregon Health & Science University
Portland, OR
Alyssa Wu, PharmD, BCPPS
Multidisciplinary AD Program Pharmacist
Rady Children’s Hospital San Diego
San Diego, CA
Disclosures of Conflict of Interest
It is the policy of AcademicCME that all faculty, instructors, and planners disclose real or apparent conflicts of interest relating to the topics of this educational activity.
The faculty reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CE activity:
| Faculty | Relationship Identified With: |
| Lawrence F. Eichenfield, MD | Consultant/Advisor: AbbVie; Almirall; Arcutis; Arena Pharmaceuticals, Aslan; Dermavant; Eli Lilly; Galderma; Incyte; Janssen; Leo Pharm; Novartis; Ortho Dermatologics; Pfizer Inc.; Regeneron; Sanofi- Genzyme
Grant/Research Support: AbbVie; Amgen Inc.; Arcutis Biotherapeutics; Corevita; Eli Lilly; Incyte; Leo Pharma; Novartis; Pfizer Inc.; Regeneron; Sanofi- Genzyme; Trevi Therapeutics Speakers Bureau: Incyte; Leo Pharm; Pfizer Inc.; Regeneron; Sanofi- Genzyme Board of Directors: Forte; Verrica |
| Jonathan Silverberg, MD, PhD, MPH
|
Consultant/Advisor: Abbvie; Afyx; Aobiome; Arena; Asana; Aslan; BioMX; Bluefin; Bodewell; Boehringer-Ingelheim; Celgene; Connect Biopharma; Dermavant; Dermira; Eli Lilly; Galderma; GlaxoSmithKline; Incyte; Kiniksa; Leo Pharma; Luna; Menlo; Novartis; Pfizer Inc.; RAPT; Regeneron; Sanofi-Genzyme
Speakers Bureau: Abbvie; Eli Lilly; Leo Pharma; Pfizer Inc.; Regeneron; Sanofi-Genzyme |
|
Eric Simpson, MD, MCR
|
Consultant/Advisor: AbbVie; Amgen Inc.; Arena Pharmaceuticals, Inc.; Benevolent AI Bio Limited; BiomX Ltd; Bluefin Biomedicine Inc; Boehringer-Ingelheim; Dermira; Eli Lilly; Evidera; ExcerptaMedica; Forte Bio RX; Galderma; GlaxoSmithKline; Incyte; Janssen; Kyowa Kirin Pharmaceutical Development; Leo Pharma; Novartis; Pfizer Inc.; Physicians World LLC; Regeneron; Roivant; Sanofi- Genzyme; Trevi Therapeutics; Valeant; WebMD
Grant/Research Support: AbbVie; Amgen Inc.; Arcutis Biotherapeutics; Corevita; Dermira; Eli Lilly; Incyte; Kyowa Kirin Pharmaceutical Development; Leo Pharma; Merck; Novartis; Pfizer Inc.; Regeneron; Sanofi- Genzyme; Trevi Therapeutics Speakers Bureau: AbbVie; Eli Lilly; Leo Pharma; Pfizer Inc.; Regeneron; Sanofi- Genzyme |
| Alyssa Wu, PharmD, BCPPS | Nothing to disclose |
Planners and Peer Reviewers
Timothy Hayes, MD, PhD; Kim Cheramie, MSN, RN-BC; Gabrielle Fiorelli, CRNP; Chelsey Benedek and Nicole McMenamin state that they or their spouse/life partner do not have any financial relationships to products or devices with any commercial interests related to the content of this activity of any amount during the past 12 months.
Accreditation Statement
In support of improving patient care, AcademicCME is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Credit Designation Statements
AcademicCME designates this enduring material for a maximum of 1.0 AMA PRA Category 1 CreditTM.
AcademicCME designates this enduring material for a maximum of 1.0 CNE Contact Hour (Provider #P0491).
AcademicCME designates this continuing education activity for 1.0 CPE Contact Hour (0.10 CEUs) of continuing pharmacy education credit (UAN JA4008190-0000-22-002-H04-P).
Participants should claim only the credit commensurate with the extent of their participation in the activity.
Financial Support
This activity has been supported by an independent educational grant from Pfizer Inc.
Disclosure of Unlabeled Use
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. AcademicCME and Pfizer Inc. do not recommend the use of any agent outside of the labeled indications.
Disclaimer
Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.
Method of Participation
In order to claim credit, participants must complete the following:
- Read the learning objectives, accreditation information and faculty disclosures at the beginning of this activity.
- Complete the Pre-Activity Questions
- Read or Review the activity content.
- Complete the Post-Activity Test Questions and Evaluation.
- Learners who receive a grade of 80% or better on the Post-Activity Test Questions and complete the Evaluation will receive appropriate credit as indicated (CME, CNE, and/or CPE credit).
- CPE credit will be posted to the learner’s CPE Monitor profile within 60 days of completion.
- CME and CNE credit will be issued appropriate certificate of completion.
- Others may request a “certificate of completion”.
- Learners should claim only the credit commensurate with the extent of their participation in the activity.
CE Inquiries/Special Needs
For all CE inquiries or special needs, please contact [email protected].
