2) A propos to our mission, our FIRST program presents a foundational review of #IBS C and D: #pathophysiology, #symptoms, #diagnosis, & classes of therapeutic options. Our inaugural expert faculty is John Damianos MD @john_damianosMD from @MayoClinicGIHep pic.twitter.com/gM4WZgMV8n
— ibs_ce (@ibs_ce) April 8, 2025
4) So–what do you know??
A 22 ♀️is diagnosed w/ #IBS_C. She asks for dietary tx to manage her symptoms. Which of the following has the strongest evidence for the ⬇️ of global IBS sx?
a. Low-FODMAP diet
b. Gluten-free diet
c. 6-food elimination diet
d. IgG-guided elimination— ibs_ce (@ibs_ce) April 8, 2025
6) 45♂️has w/u for chronic abd pain & alternating bowel habits. Blood & stool testing, CT abd & #colonoscopy all normal. Which mechanism is likely the strongest contributor to his sx?
a. immune dysregulation
b. parasitic infection
c. visceral ⬆️sensitivity
d. rapid gut transit— ibs_ce (@ibs_ce) April 8, 2025
8) #IBS risk factors
👩female sex
❗️early life trauma
🧬genetics
🦠enteric infections
🍩Western diet
🧠anxiety, depression, PTSD
🚬smoking
💊antibiotic use
See 🔓 https://t.co/LvBTrm9gWV pic.twitter.com/oZZrrYDp31— ibs_ce (@ibs_ce) April 8, 2025
10) Post-infectious IBS: GI infections ➡️#IBS in 14.5%
➗OR 4.3
🦠parasites most common, then bacteria & viruses
🦠Campylobacter (20.7%), Proteobacteria, & SARS-CoV-2 have highest risk
🗓️40% persistence at 5 years
*⃣risk factors: female sex & anxiety
See https://t.co/5oT5asGOAe pic.twitter.com/aOJYoky71g— ibs_ce (@ibs_ce) April 8, 2025
12) Categorize type #IBS by predominant stool form as per 🔓 https://t.co/ZZytc1oBJa pic.twitter.com/ZNWWFCxrjx
— ibs_ce (@ibs_ce) April 8, 2025
14) #Enteric infections leading to a loss of immune tolerance to food antigens has been hypothesized to be an important contributor to symptoms in a subset of #IBS patients. See
https://t.co/2WmKkflPXy ANDhttps://t.co/OcuOvNnUym pic.twitter.com/7Mp0Sr9bTd— ibs_ce (@ibs_ce) April 8, 2025
16) Treatment of #IBS should be #MULTIDISCIPLINARY, as this has been associated with better outcomes and patient satisfaction
🤝GI
🤝PCP
🤝Nutrition
🤝Psychiatry/Psychology
🤝Pelvic floor physical therapy
See 🔓 https://t.co/HlWwhuhTKT
AND
🔓 https://t.co/P6TuoZdSvU pic.twitter.com/vLZJF0zlZf— ibs_ce (@ibs_ce) April 8, 2025
18) .@AmerGastroAssn clinical decision support tool on #IBS management pic.twitter.com/dzFFUl1COl
— ibs_ce (@ibs_ce) April 8, 2025
20) #FODMAP foods are common triggers because they are fermented by gut microbiota, leading to gas generation & luminal water retention, which causes bloating, pain, & diarrhea in those with visceral hypersensitivity
See https://t.co/ZDAlSGU4Ur pic.twitter.com/oMC8H9oD0m— ibs_ce (@ibs_ce) April 8, 2025
22) The low-#FODMAP diet is superior to standard-of-care medical therapy. See https://t.co/P6NV2bfVDh pic.twitter.com/bMLpzYhr9U
— ibs_ce (@ibs_ce) April 8, 2025
24) #FODMAP-lite? Multiple studies have shown that certain FODMAPs disproportionately cause symptoms, and restricting only these may be as effective as the more restrictive diet. See
https://t.co/vCga2uNtRE AND https://t.co/nCpy7T3jnE pic.twitter.com/s5nBa3Lgsj— ibs_ce (@ibs_ce) April 8, 2025
24) #FODMAP-lite? Multiple studies have shown that certain FODMAPs disproportionately cause symptoms, and restricting only these may be as effective as the more restrictive diet. See
https://t.co/vCga2uNtRE AND https://t.co/nCpy7T3jnE pic.twitter.com/s5nBa3Lgsj— ibs_ce (@ibs_ce) April 8, 2025
28) #Probiotics are recommended in some #guidelines but not in others, due to conflicting evidence. pic.twitter.com/CMCke0Jsez
— ibs_ce (@ibs_ce) April 8, 2025
30) #Pharmacotherapy for #IBS should target the patient’s primary disturbance: sensory or motor. See https://t.co/bmYnoHhAG6 pic.twitter.com/QJEAurdeFT
— ibs_ce (@ibs_ce) April 8, 2025
32) #Rifaximin is a non-absorbed antibiotic for #IBS_D that targets dysbiosis
See 🔓 https://t.co/QqAlulxVHH pic.twitter.com/cEuoW78TL3— ibs_ce (@ibs_ce) April 8, 2025
34) #Neuromodulators target the SENSORY aspect of #IBS symptoms.
See 🔓 https://t.co/WstyRP0ztc pic.twitter.com/72kSmctUdb— ibs_ce (@ibs_ce) April 8, 2025
36) Psychological-based therapies such as cognitive behavioral therapy and gut-directed hypnotherapy are effective for #IBS, as per
🔓 https://t.co/5DIxTx3rOQ
AND https://t.co/m1Fbl47VAz pic.twitter.com/eqKW2AlDg7— ibs_ce (@ibs_ce) April 8, 2025
38) And that's it! You just earned 0.75 hr 🆓CE/#CME. Claim your certificate right now at https://t.co/C1aSWuMdZ3 and then 🖱️ that "FOLLOW" button for more expert-authored programs. Thanks to @john_damianosMD for getting @ibs_ce off on the right 🦶!
— ibs_ce (@ibs_ce) April 8, 2025
