Scientific Overview: The Pathology, Biology, and Molecular Genetics of SMA

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Course Information

Therapautic Area: Neurology
Format(s): Webcast
Credit(s): 0.50 AMA PRA Category 1 Credit(s)™: 0.50 CNE Contact Hour(s)
Activity Dates: February 9, 2018 - February 8, 2019

 

Program Overview

In this module of a Five-Part Expert Interview Series, Dr. John Brandsema, along with Dr. Basil Darras, will review the pathology, biology and molecular genetics of spinal muscular atrophy (SMA). This discussion will provide clinicians with a better understanding of the science of spinal muscular atrophy and how it relates to patient care.

Target Audience

Neurologists, pediatricians, primary care physicians, internists, nurse practitioners, nurses, and other healthcare professionals involved in the management of patients with SMA

Learning Objectives

  1. Review the current science of SMA including the biology, pathology and molecular genetics
  2. Incorporate scientific updates when treating patients with SMA

Faculty

Darras-BasilBasil T. Darras, MD
Associate Neurologist-in-Chief
Chief-Division of Clinical Neurology
Director, Neuromuscular Center and Spinal Muscular Atrophy Program
Boston Children’s Hospital
Professor of Neurology
Harvard Medical School
Boston, MA

 

BrandsemaJohn F. Brandsema, MD
Attending Physician
Neuromuscular/General Neurology & Electromyography
Neuromuscular Education Director and
Neuromuscular Section Head
Children’s Hospital of Philadelphia
Philadelphia, PA

 

Disclosures of Conflict of Interest

It is the policy of AcademicCME that all faculty, instructors, and planners disclose real or apparent conflicts of interest relating to the topics of this educational activity.

The faculty reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME/CNE activity:

Faculty Relationship Identified With:
Basil T. Darras, MD Consultant/Advisor: AveXis, Inc.; Biogen; Bristol-Myeres Squibb Company; Cytokinetics, Inc.; Marathon Pharmaceuticals LLC; PTC Therapeutics;F. Hoffmann-La Roche Ltd; Santhera Pharmaceuticals; Sarepta TherapeuticsGrant/Research Support: National Institutes of Health; National Institute of Neurological Disorders and Stroke; Slaney Family Fund for SMA; Working on Walking Fund; SMA Foundation; CureSMA; Ionis Pharmaceuticals, Inc.Speakers Bureau: Biogen
John F. Brandsema, MD Consultant/Advisor: AveXis, Inc.; Biogen; Cytokinetics, Inc.
Speakers Bureau: Biogen

Planners, Managers, Reviewers


Timothy Hayes, MD, PhD; Emma Boring; Chelsey Benedek and Kim Cheramie, MSN, RN-BC hereby state that they or their spouse/life partner do not have any financial relationships to products or devices with any commercial interests related to the content of this activity of any amount during the past 12 months.

Accreditation Statements

AcademicCME is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

AcademicCME is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission (ANCC) on Accreditation. AcademicCME’s ANCC provider number is P0491.

Credit Designation Statements

AcademicCME designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

AcademicCME designates this enduring material for a maximum of 0.50 CNE contact hours.

Financial Support

This activity has been supported by an independent educational grant from Biogen.

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. AcademicCME and Biogen. do not recommend the use of any agent outside of the labeled indications.

Disclaimer

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

Method of Participation

1. Read the learning objectives, accreditation information and faculty disclosures at the beginning of this activity.
2. Complete the Pre-Activity Questions.
3. Read or Review the activity content.
4. Complete the Post-Activity Test Questions and Evaluation.
5. Healthcare providers who receive a grade of 70% or better on the Post-Activity Test Questions and who complete the Evaluation will receive a CME/CNE Certificate.
6. All other participants who receive a grade of 70% or better on the Post-Activity Test Questions and who complete the Evaluation will receive a Certificate of Participation.
7. Healthcare providers should claim only the credit commensurate with the extent of their participation in the activity.
8. 60 minutes of participation = 1 CNE contact hour

CE Inquiries/Special Needs

For all CME/CNE inquiries or special needs, please contact admin@academiccme.com.

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